A team of Australian researchers, led by Dr Camilla Beale from the Illawarra Health and Medical Research Institute, examined the effects of CBD in regards to repairment and reduction of the adverse neuroanatomic effects in the hippocampus region of the brain. They found that CBD has neuro-restorative effects.
Many cannabis users are aware of the fact that frequent and prolonged use of cannabis is associated with hippocampal damage, a side-effect that is attributed to THC — tetrahydrocannabinol.
Eighteen participants (predominantly young white males), who are also regular pot users, were given a daily dose of 200 mg of CBD for approximately 10 weeks.
Structural magnetic resonance imaging was used before the study started, and once more when it was finished. The team in charge of the research assessed the changes in each of the 12 sub-fields of hippocampus.
The study showed that the size of parasubiculum, presubiculum and subiculum (which are all a part of the left subicular complex of the hippocampus) had all increased significantly from the use of CBD. Participants also reported feeling less euphoria while consuming cannabis, an effect that can be attributed to CBD’s unique pharmacological action.
More frequent users experienced greater growth in these important sections of the brain, in comparison the to participants who weren’t so dependent on cannabis.
Dr. Beale concluded that CBD holds great potential for treatment of patients suffering from conditions such as schizophrenia, Alzheimer’s disease and depression, simply because of its protective and restorative effects.