Actor and weed enthusiast Seth Rogen is hosting a cannabis-themed charity festival to help raise awareness about Alzheimer’s disease.
Rogen and his wife Lauren’s Alzheimer’s organization Charity for Hilarity will hold its next event in Los Angeles on September 14.
Although the exact details of the marijuana program haven’t been revealed, Rogen announced in the promotional video that “We here at Hilarity for Charity love to fight Alzheimer’s disease, but we also love rides, food, alcohol, and weed! We also love trying to be good people so that in the event there is an afterlife, we don’t go to hell.”
The charity event’s line-up of comedians includes Adam Devine, Andrew Rannells, Ben Feldman, Casey Wilson, Ilana Glazer, Regina Hall, and many more. Meanwhile, skateboarder Tony Hawk and musician Anderson Paak will have a performance of their own at the event.
Rogen founded the charity in 2012 after his mother-in-law was diagnosed with Alzheimer’s. After witnessing what he described in an interview as a “brutal” disease, the couple decided to dedicate time to fight the chronic neurodegenerative disease which affects about 5.8 million Americans.
Medical marijuana can be used to alleviate symptoms of Alzheimer’s such as dementia. Several studies have indicated that tetrahydrocannabinol or THC, as well as some other cannabis compounds, appear to remove toxic clumps of amyloid beta protein in the brain, believed to lead to Alzheimer’s disease.
One such study conducted by scientists at the Salk Institute for Biological Studies in California found that THC may play a role in the removal of these toxic clumps associated with Alzheimer’s, paving the way for further research and potential new drugs.
“Although other studies have offered evidence that cannabinoids might be neuroprotective against the symptoms of Alzheimer’s, we believe our study is the first to demonstrate that cannabinoids affect both inflammation and amyloid beta accumulation in nerve cells,” senior author of the study Professor David Schubert said.
Currently, 13 states in the US allow medical marijuana as a means of treating Alzheimer’s disease, according to Leafly’s list of qualifying conditions by state from October 2018.