Treating Crohn’s with Marijuana is Possible: Here’s How

Crohn’s Disease is a terribly aggravating autoimmune illness, manifested by everyday troubles that can break the spirit of even the toughest individuals.

Battling this sickness requires time and extreme patience, but numerous studies have shown that cannabis can have truly wonderful effects in aiding Crohn’s patients.

First and foremost, we should further elaborate on what exactly is Crohn’s Disease, and what are the main symptoms surrounding this illness.

What is Crohn’s Disease?

Crohn’s Disease is an inflammatory bowel disease, for which the cause unfortunately hasn’t been identified yet.

The most frequent manifestation is the inflammation of the gastrointestinal tract (GI), and usually the most affected area is the ileum, which is located at the end of the small intestine and in the beginning of the colon.

The most accepted theory to date is that the cause is in direct correlation with genetic flaws that distort the programming of the immune system and that these flaws can be brought about by various outside factors and influences.

As previously mentioned above, the biggest issue with Crohn’s Disease is the constant inflammation of the gastrointestinal tract. While inflamed, the stomach is unable to absorb all the necessary nutrients humans require to function properly.

This symptom is also called wasting, because all the solid foods and liquids just pass through the organism, causing really serious damage, with the accompanying relentless weight loss.

The main symptoms of Crohn’s Disease

The symptoms can differ depending on what part of the GI tract is affected, but the most frequent include:

  • Bloody stool
  • Severe diarrhea
  • Severe abdominal pain
  • Fatigue
  • Fever
  • Wasting (inability to properly absorb nutrients, resulting in weight loss)

Pharmaceuticals vs cannabis in treating Crohn’s disease?

Marijuana and pills

Classical pharmaceutical drugs tackle Crohn’s by trying to prevent the inflammation by restraining the immune system from constantly attacking the GI tract. This is a common medical treatment, but in the case of Crohn’s disease, it is not very effective.

On the other hand, cannabinoids (the active chemical compounds in cannabis), prevent the immune system from discharging inflammatory proteins and instead activate proteins that battle the inflammation.

The reason behind this occurrence lies in the fact that the human body possesses a great number of cannabinoid receptors throughout the GI tract, in the network called the endocannabinoid system (ECS).

The ECS is constructed out of cell receptors, their matching molecules, and the proteins that create and dissolve these molecules.

Cannabinoid receptors are particularly located on cells that are in charge of immunity, which exemplifies how valuable the endocannabinoid system is for maintaining overall immune function.

This study shows that, while under inflammation from various irritable bowel diseases, the human body produces a smaller amount of endocannabinoids than usual. and that some cannabinoid receptors are unregulated, which is a sign that the GI tract desires a greater cannabinoid input.

Even though the direct correlation between Crohn’s Disease and the effect the endocannabinoid system has on it is still distant from absolute comprehension, the discoveries so far indicate that the therapies which include cannabinoids are quite effective in sending this illness into remission.

Which cannabinoids help with Crohn’s disease?

The most important cannabinoids for battling Crohn’s Disease are THC and CBD. Tetrahydrocannabinol (THC) is in charge of pain relief, suppressing spasms, while also significantly increasing the patient’s appetite.

On the other hand, Cannabidiol (CBD) is in charge of reducing inflammation, causes relaxation and general sedation, while also lowering anxiety and stress, which is more than useful for Crohn’s Disease patients who experience frequent stomach spasms and excruciating pain in the general abdomen region.

Most cannabis strains usually have a far greater concentration of THC in comparison to CBD, and because high levels of THC also brings about euphoria and possible anxiety and paranoia, patients should consume strains that also have a large quantity of CBD (besides THC), no matter if they smoke marijuana, or use one of the other ways of ingesting cannabinoids, like vaping, oils or edibles/medibles.

CBD also offers great assistance by attacking bacterial infections which are relatively common in people who struggle with continual GI inflammations.

It should be noted that finding strains which contain large doses of CBD can be quite difficult in countries that haven’t yet legislated the use of medicinal marijuana.

Another study was undertaken in 2013 in Israel, and it showed that 45% of the participants had “total remission” of their Crohn’s Disease, after a 8 week period of 115 mg of THC on a daily basis.

Also, a great example of treating Crohn’s Disease is done by Mara Gordon, who’s a specialist on treating serious illnesses with cannabis, with an experience of over 600 patients under her belt.

In her opinion, the best dosage of cannabinoids are 30 mg of THC and 15 mg of CBD per day, although this will be pretty hard to achieve without most strains.

5 best cannabis strains for Crohn’s disease

Before we jump into the exact process of figuring out the dosage, check out our 5 picks for aiding patients with Crohn’s:

Medicine Man (THC 20%, CBD 1%)

Medicine man has a high concentration of both THC and CBD, which is quite helpful for this particular disease. This is, in fact, an Indica dominant hybrid, famous for its potent high that affects the body, producing the, now famous, couchlock effect.

Chemo (THC 18%, CBD 20%)

As the name suggests, Chemo offers heavy sedation, perfect for cramps and muscle spasms that frequently plague Crohn patients. This is, also, one of the few strains that offer a therapeutically perfect 1:1 THC vs CBD ratio.

Harlequin OG (THC 35%, CBD 30%)

With high levels of both CBD and THC, Harlequin is truly amazing for both pain and stress, because large amounts of CBD cannabinol can battle the exhilaration provided by THC. Even though this is a Sativa dominant hybrid, Harlequin OG is sure to tackle even the gnarliest Crohn’s symptoms.

Hash Plant (THC 13%, CBD 19%)

Amazing for inflammation and pain, Hash Plant has a powerful body effect, while also affecting the mind with gentle euphoria. Packing on the same 50/50 cannabinoid ratio, Hash Plant found its use in numerous medicinal cases, including Crohn’s disease.

Confidential Cheese (THC 19%, 0.22%)

Another great strain for abolishing spasms and cramps, it is a 50/50 Indica Sativa hybrid. With its parents being LA Confidential and Exodus Cheese, Confidential Cheese is also very adequate for patients with pain and stress.

Self administering cannabis for treating Crohn’s disease

My first advice is to get an actual doctor to look at your case and prescribe proper cannabis dosage. If you are, however, living in an area where you don’t have a doctor nearby, or you’re growing your own plants, read on.

Figuring out the proper therapeutic cannabis dosage is pretty difficult for beginner users, but is, fortunately, easily explained.

If you buy, for example, two grams of Harlequin OG (in a dispensary of course), you will get the exact THC and CBD content information on the label itself.

Remember: studies have shown that Crohn’s disease patients could benefit from 30-100 mg of THC and 30-60 mg of CBD per day.

Harlequin generally has around 35% of THC and 30% CBD, which is perfect.

Considering that 1 gram = 1,000 mg, and using a simple percentage calculator, we can calculate that we would need to smoke exactly 0.2 grams of Harlequin OG every day, to get the biggest benefits.

Percentage calculator

To repeat the process I used:

  1. Find out what are the THC and CBD percentages of your strain
  2. Go to Percentage Calculator
  3. Type in the THC percentage in the first box
  4. Type in the volume (in milligrams) in the second box
  5. Reduce and dial down the volume until the results are 30-100
  6. The result in the second box is exactly how much weed you need every day in milligrams

Like in any other topic, medical opinions always vary, from doctor to doctor. However, the studies have proved that Crohn’s Disease can be positively affected, or placed entirely under remission by precisely determining and executing proper cannabis treatment.

Whether you go down this green route is entirely up to you.


A passionate cannabis enthusiast ever since his late teens, Marco usually writes about 420 culture, health and weed basics. You can find him discussing various conspiracy theories with his peers.

2 thoughts on “Treating Crohn’s with Marijuana is Possible: Here’s How

  1. Our experience with CBD has been amazing. Since we first started using it, we have noticed an amazing health improvement in my son’s life. His Crohn’s has been in remission since he has started the water soluble BioCBD. He had never been in remission before. He was only controlled with his other medications, but never in remission. The other medications he has used in the past have also left damaging effects, whether they were instant or long lasting. I’d say this is truly a blessing to our family!

    • Thank you very much May for leaving this comment, and I’m extremely happy that your son is feeling better 🙂

      It’s quite important for skeptics who still believe marijuana is just a getting-high tool to hear about real life situations like yours, where lives were changed because of the healing qualities of cannabis and CBD.

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